717107-19-2Relevant academic research and scientific papers
PHTHALAZINE DERIVATIVES PHOSPHODIESTERASE 4 INHIBITORS
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Page 16, (2008/06/13)
Compounds of formula (I) wherein R is methyl or difluoromethyl; X is a methylene group, ethylene, -CH=CH-, -O-CH2-, -O-(CH2)2, -O-(CH2)3-, -NH-SO2-(CH2)3-, -NH-CO-(CH2)2-, -NH-CO-(CH2)3-, N-(ethane-sulfonylamino) pyperazinyl, the N-oxidised derivatives of -CH2-CH-NH2| the compounds of formula I and the pharmaceutically acceptable salts thereof are described.The compounds of formula I are PDE 4 inhibitors.
