717111-14-3

Upstream product

• 5927-18-4 trimethyl phosphonoacetate 
• 263770-43-0 (3R,4S)-4-(4-chlorophenyl)-1-methylpiperidine-3-carbaldehyde 
• 263769-22-8 (+)-methyl 4β-(4-chlorophenyl)-1-methylpiperidine-3α-carboxylate 
• 263769-24-0 (+)-4β-(4-Chlorophenyl)-3α-(hydroxymethyl)-1-methylpiperidine 

Downstream Products

• 717109-67-6 3-[(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-yl]-propionic acid 
• 717111-95-0 3-[(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-yl]-propionyl chloride 
• 717111-36-9 3-[(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-yl]-propan-1-ol 
• 717111-20-1 3-[(3R,4S)-4-(4-Chloro-phenyl)-1-methyl-piperidin-3-yl]-propionic acid methyl ester 

Relevant academic research and scientific papers

Synthesis, molecular modeling, and biological studies of novel piperidine-based analogues of cocaine: Evidence of unfavorable interactions proximal to the 3α-position of the piperidine ring

A qualitative model for the binding pocket proximal to the 3α-substituent of the piperidine-based monoamine transporter ligands was proposed and tested. Based on this model, a new series of druglike 3α-modified piperidine-based analogues of cocaine were d