71745-63-6Relevant academic research and scientific papers
Total Synthesis of Pyrolaside B: Phenol Trimerization through Sequenced Oxidative C?C and C?O Coupling
Kozlowski, Marisa C.,Neuhaus, William C.
supporting information, p. 7842 - 7847 (2020/04/03)
A facile method to oxidatively trimerize phenols using a catalytic aerobic copper system is described. The mechanism of this transformation was probed, yielding insight that enabled cross-coupling trimerizations. With this method, the natural product pyro
MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS
-
Paragraph 00641, (2017/08/01)
Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidase (SpsB), an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.
