71764-93-7Relevant academic research and scientific papers
Proline derived guanidine catalysts forge extensive H-bonded architectures: A solution and solid state study
Al-Taie, Zahraa S.,Anetts, Simon R.,Christensen, Jeppe,Coles, Simon J.,De Kleijne, Frank F. J.,Evans, Daniel M.,Horton, Peter N.,Jones, Leigh F.,Ledbetter, Shaun M.,Mehdar, Yassin T. H.,Murphy, Patrick J.,Wilson, Jack A.
, p. 22397 - 22416 (2020/07/14)
The preparation of a range of amino acid derived guanidine organocatalysts is reported together with their application to the Michael addition of 2-hydroxy-1,4-napthoquinone to β-nitrostyrene, achieving a maximum ee of 56%. Some insight into the mechanism was sought by using X-ray crystallography and a detailed study of the intra- and intermolecular hydrogen bonding is reported. This journal is
ANTIBIOTIC COMPOUNDS
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Page/Page column 109; 110, (2018/03/25)
The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.
