71765-80-5

Basic information

• Product Name: 6-Methoxy-7-(3-methyl-2-butenyloxy)-8-hydroxy-2H-1-benzopyran-2-one
• Synonyms: 6-Methoxy-7-(3-methyl-2-butenyloxy)-8-hydroxy-2H-1-benzopyran-2-one;8-Hydroxy-6-methoxy-7-[(3-methyl-2-butenyl)oxy]-2H-1-benzopyran-2-one
• CAS NO: 71765-80-5
• Molecular Formula: C₁₅H₁₆O₅
• Molecular Weight: 276.28
• Mol File: 71765-80-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 6-Methoxy-7-(3-methyl-2-butenyloxy)-8-hydroxy-2H-1-benzopyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methoxy-7-(3-methyl-2-butenyloxy)-8-hydroxy-2H-1-benzopyran-2-one(71765-80-5)
• EPA Substance Registry System: 6-Methoxy-7-(3-methyl-2-butenyloxy)-8-hydroxy-2H-1-benzopyran-2-one(71765-80-5)

Safety Data

• Hazardous Substances Data: 71765-80-5(Hazardous Substances Data)

Upstream product

• 2103-57-3 2,3,4-trimethoxybenzaldehyde 
• 667876-16-6 2,3-di[(isopropyl)oxy]-4-methoxybenzaldehyde 
• 4055-69-0 2,3-dihydroxy-4-methoxybenzaldehyde 
• 574-84-5 7,8-dihydroxy-6-methoxy-2H-1-benzopyran-2-one 
• 870-63-3 prenyl bromide 

Downstream Products

• 28843-40-5 6-methoxy-7,8-methylenedioxycoumarin 
• 574-84-5 7,8-dihydroxy-6-methoxy-2H-1-benzopyran-2-one 

Relevant articles and documents

Synthesis of purpurasol, a highly oxygenated coumarin from Pterocaulon purpurascens

Purpurasol 1, a 6,7,8-trioxygenated coumarin, isolated from Pterocaulon purpurascens (Asteraceae) and Haplophyllum obtusifolium (Rutaceae), was synthesized for the first time by a three-step synthesis starting from the natural coumarin fraxetin. This synthesis confirmed unambiguously the structure of purpurasol 1 and obtusifol.

Total syntheses of the coumarin-containing natural products pimpinellin and fraxetin using Au(I)-catalyzed intramolecular hydroarylation (IMHA) chemistry

The title natural products (1 and 2, respectively) have been synthesized by Au(I)-catalyzed intramolecular hydroarylation (IMHA) of the relevant aryl propiolate esters (e.g., 13), which were themselves formed by reaction of the corresponding phenols with either 3-(trimethylsilyl)propiolic acid or propiolic acid and N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride or dicyclohexylcarbodiimide. (±)-Purpurasol (3) was readily derived from fraxetin (2) by established procedures.