717919-46-5Relevant articles and documents
Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain
Pelloux-Léon, Nadia,Fkyerat, Abdellatif,Piripitsi, Antonia,Tertiuk, Wasyl,Schunack, Walter,Stark, Holger,Garbarg, Monique,Ligneau, Xavier,Arrang, Jean-Michel,Schwartz, Jean-Charles,Ganellin, C. Robin
, p. 3264 - 3274 (2007/10/03)
4-(3-Aryloxypropyl)-1H-imidazoles, which possess a meta-positioned substituent in the aryl ring, have been synthesized and tested for activity at histamine H3 receptors. The compounds having a CN, Me, or Br substituent were found to be antagoni