71804-70-1

Basic information

• Product Name: Benzene, (3-iodo-2-propenyl)-
• CAS NO: 71804-70-1
• Molecular Formula: C9H9I
• Molecular Weight: 244.075
• Mol File: 71804-70-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, (3-iodo-2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (3-iodo-2-propenyl)-(71804-70-1)
• EPA Substance Registry System: Benzene, (3-iodo-2-propenyl)-(71804-70-1)

Safety Data

• Hazardous Substances Data: 71804-70-1(Hazardous Substances Data)

Upstream product

• 3020-28-8 (iodomethyl)triphenylphosphonium iodide 
• 122-78-1 phenylacetaldehyde 
• 74-88-4 methyl iodide 
• 141694-60-2 1,1-diiodo-3-phenylpropane 
• 141694-57-7 Trifluoro-methanesulfonic acid 3-phenyl-1-trifluoromethanesulfonyloxy-propyl ester 
• 104-53-0 3-phenyl-propionaldehyde 

Relevant articles and documents

Copper-catalyzed cross-coupling of amino acid-derived amides with (Z)-vinyl iodides: Unexpected solvent effect and preparation of plocabulin

A copper-catalyzed cross-coupling reaction of amino acid-derived amides and (Z)-vinyl iodide was studied to improve a key step in the synthesis of plocabulin, a novel microtubule destabilizer agent of marine origin. The study revealed a profound solvent effect with 1,2-dimethoxyethane (DME), which gave consistently high yields across a large variety of the amide and (Z)-vinyl iodide substrates. The protocol was successfully utilized in the preparation of plocabulin and provided a significantly improved yield.

A new Procedure for the Synthesis of (E)-1-iodo-1-alkenes

(E)-1-iodo-1-alkenes 4 can be prepared stereoselectively from aldehydes 1 via IH-elimination of 1,1-di-iodoalkanes 3 with DBU. Key words: Vinyl iodide; diiodoalkane; elimination; stereoselectivity.