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Monactin is a member of the macrotetrolide complex produced by a range of Streptomyces species. It is a monovalent cation ionophore with high selectivity for ammonium and potassium. Monactin has not previously been available for intensive investigation, but it has been reported to inhibit T-cell proliferation induced by IL-2 and cytokine production at nanomolar levels for IL-2, IL-4, IL-5, and IFN-γ.

7182-54-9

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7182-54-9 Usage

Uses

Used in Pharmaceutical Industry:
Monactin is used as a pharmaceutical agent for its immunosuppressive properties. It inhibits T-cell proliferation and cytokine production, making it a potential candidate for the treatment of autoimmune diseases and transplantation.
Used in Research Applications:
Monactin is used as a research tool for studying the mechanisms of T-cell proliferation and cytokine production. Its ability to inhibit these processes at nanomolar levels makes it a valuable compound for investigating the role of T-cells in immune responses and the development of new therapeutic strategies.
Used in Drug Development:
Monactin is used as a lead compound in the development of new drugs targeting T-cell proliferation and cytokine production. Its unique properties as a monovalent cation ionophore with high selectivity for ammonium and potassium make it a promising candidate for the development of novel immunosuppressive agents and therapies for autoimmune diseases and transplantation.

Check Digit Verification of cas no

The CAS Registry Mumber 7182-54-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,8 and 2 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7182-54:
(6*7)+(5*1)+(4*8)+(3*2)+(2*5)+(1*4)=99
99 % 10 = 9
So 7182-54-9 is a valid CAS Registry Number.
InChI:InChI=1/C41H66O12/c1-9-29-21-33-13-17-36(52-33)27(7)40(44)48-23(3)19-31-11-15-34(50-31)25(5)38(42)46-22(2)18-30-10-14-35(49-30)26(6)39(43)47-24(4)20-32-12-16-37(51-32)28(8)41(45)53-29/h22-37H,9-21H2,1-8H3

7182-54-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name Monactin

1.2 Other means of identification

Product number -
Other names Nonactin,5-demethyl-5-ethyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7182-54-9 SDS

7182-54-9Upstream product

7182-54-9Downstream Products

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