Cas 71831-09-9,Avermectin B1a monosaccharide

71831-09-9

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Basic information

Product Name: Avermectin B1a monosaccharide
Synonyms: 5-O-Demethyl-4'-O-de(2,6-dideoxy-3-O-methyl-α-L-glucopyranosyl)avermectin A1a;Avermectin B1a monosaccharide
CAS NO:71831-09-9
Molecular Formula: C41H60O11
Molecular Weight: 728.92
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Avermectin B1a monosaccharide(CAS DataBase Reference)
NIST Chemistry Reference: Avermectin B1a monosaccharide(71831-09-9)
EPA Substance Registry System: Avermectin B1a monosaccharide(71831-09-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 71831-09-9(Hazardous Substances Data)

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71831-09-9 Usage

Uses

Used in Animal Health:
Avermectin B1a monosaccharide is used as an anthelmintic agent for the treatment and control of nematode infections in animals. It is a potent inhibitor of nematode larval development, but lacks paralytic activity.
Used in Environmental Applications:
Despite the importance of avermectin as an anthelmintic in animal health, there are few published reports of the biological activity or the levels of Avermectin B1a monosaccharide in animals or in the environment. Further research is needed to understand its potential applications and impact in environmental settings.

Check Digit Verification of cas no

The CAS Registry Mumber 71831-09-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,8,3 and 1 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 71831-09:
(7*7)+(6*1)+(5*8)+(4*3)+(3*1)+(2*0)+(1*9)=119
119 % 10 = 9
So 71831-09-9 is a valid CAS Registry Number.

71831-09-9Upstream product

71831-09-9Downstream Products

71831-09-9Relevant academic research and scientific papers

Synthesis, biological activities and structure?'activity relationships for new avermectin analogues

Zhang, Jian,Nan, Xiang,Yu, Hai-Tao,Cheng, Pi-Le,Zhang, Yan,Liu, Ying-Qian,Zhang, Shao-Yong,Hu, Guan-Fang,Liu, Huanxiang,Chen, An-Liang

, p. 422 - 432 (2016)

In an effort to discover new molecules with good insecticidal activities, more than 40 new avermectin derivatives were synthesized and evaluated for their biological activities against three species of arachnids, insects and nematodes, namely, Tetranychus

Avermectin monosaccharide compound and its preparation and use

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Paragraph 0038-0045; 0054-0059, (2017/08/31)

The invention relates to the technical field of insecticidal pesticides, in particular to an avermectin monosaccharide compound, as well as a preparation method and application thereof. An oleandrose base is removed from avermectin through chemical modification, so as to obtain the avermectin monosaccharide compound. Compared with the prior art, the invention has the advantages that compared with common avermectin products, the avermectin monosaccharide compound used as an insecticide has the characteristics of high efficacy, wide insecticidal spectrum, long lasting period, no residual and no pollution, and also has the advantages of quick effect and zero resistance; particularly, the activity is extremely high for lepidopteron larva and common pests such as mites, both the stomach poisoning action and the contact action are achieved, and highly reliable and stable control effects can be achieved with an extremely low dosage; moreover, besides the fact that the insecticidal activity is remarkably higher than that of common avermectin products, the insecticidal scope of the avermectin monosaccharide compound almost covers adults and spawns of all agriculture-related nematodes and arthropods, and the destructive and fatal efficacy is remarkable. Therefore, the avermectin monosaccharide compound is applicable for being promoted and applied in related fields.

The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility

Zhang, Changsheng,Albermann, Christoph,Fu, Xun,Thorson, Jon S.

, p. 16420 - 16421 (2007/10/03)

The glycosyltransferase AveBI, which is involved in the biosynthesis of the macrolide antihelmintic avermectin (AVM), was characterized in vitro. AveBI was confirmed to catalyze two separate iterative additions of l-oleandrose, and the reversibility of AveBI-catalyzed reaction was also demonstrated. Investigation of sugar nucleotide specificity revealed 10 unique sugar nucleotide substrates which, in combination with five distinct aglycones, led to the production of 50 differentially glycosylated AVM variants. Copyright

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