71835-59-1Relevant academic research and scientific papers
α-Arylation, α-arylative esterification, or acylation: A stoichiometry-dependent trichotomy in the Pd-catalyzed cross-coupling between aldehydes and aryl bromides
Nareddy, Pradeep,Mazet, Clement
, p. 2579 - 2583 (2013)
Three′s company: The selective α-arylation and α-arylative esterification of linear and branched aldehydes is reported for a variety of bromoarenes. The acylation of aryl bromides can be achieved with linear aldehydes (see scheme). All these transformations were performed with a single [(N-heterocyclic carbene)Pd] catalyst through adjustment of the stoichiometry of the reagents and the appropriate base. Copyright
Palladium-catalyzed α-arylation of aldehydes with bromo- and chloroarenes catalyzed by [{Pd(allyl)Cl}2] and dppf or Q-phos
Vo, Giang D.,Hartwig, John F.
supporting information; experimental part, p. 2127 - 2130 (2009/02/06)
(Chemical Equation Presented) Pd source matters: A general method for palladium-catalyzed a-arylation of aldehydes (see scheme) was developed to couple linear and branched aldehydes with electron-poor and electron-rich bromo- and chloroarenes.
