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H-TRP-ASP-OH is a peptide molecule composed of the amino acids tryptophan (TRP) and aspartic acid (ASP) linked in a sequence. This molecule is significant in research and drug development due to its potential to modulate various biological functions. Tryptophan, an essential amino acid, is crucial for protein synthesis and serves as a precursor for the neurotransmitter serotonin. Aspartic acid, a non-essential amino acid, plays a role in energy production and neurotransmitter function. The combination of these amino acids in H-TRP-ASP-OH may influence multiple physiological processes and contribute to the development of new pharmaceuticals.

71835-78-4

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71835-78-4 Usage

Uses

Used in Pharmaceutical Development:
H-TRP-ASP-OH is utilized as a pharmaceutical candidate for modulating biological functions due to its potential influence on physiological processes.
Used in Research:
H-TRP-ASP-OH is used as a research tool to study the effects of amino acid sequences on biological systems and their potential applications in drug development.

Check Digit Verification of cas no

The CAS Registry Mumber 71835-78-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,8,3 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 71835-78:
(7*7)+(6*1)+(5*8)+(4*3)+(3*5)+(2*7)+(1*8)=144
144 % 10 = 4
So 71835-78-4 is a valid CAS Registry Number.

71835-78-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name H-TRP-ASP-OH

1.2 Other means of identification

Product number -
Other names L-TRYPTOPHYL-L-ASPARTIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:71835-78-4 SDS

71835-78-4Downstream Products

71835-78-4Relevant academic research and scientific papers

Translation of Mycobacterium Survival Strategy to Develop a Lipo-peptide based Fusion Inhibitor**

Sardar, Avijit,Lahiri, Aritraa,Kamble, Mithila,Mallick, Amirul I.,Tarafdar, Pradip K.

, p. 6101 - 6106 (2021)

The entry of enveloped virus requires the fusion of viral and host cell membranes. An effective fusion inhibitor aiming at impeding such membrane fusion may emerge as a broad-spectrum antiviral agent against a wide range of viral infections. Mycobacterium survives inside the phagosome by inhibiting phagosome–lysosome fusion with the help of a coat protein coronin 1. Structural analysis of coronin 1 and other WD40-repeat protein suggest that the trp-asp (WD) sequence is placed at distorted β-meander motif (more exposed) in coronin 1. The unique structural feature of coronin 1 was explored to identify a simple lipo-peptide sequence (myr-WD), which effectively inhibits membrane fusion by modulating the interfacial order, water penetration, and surface potential. The mycobacterium inspired lipo-dipeptide was successfully tested to combat type 1 influenza virus (H1N1) and murine coronavirus infections as a potential broad-spectrum antiviral agent.

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