71845-14-2Relevant academic research and scientific papers
A new synthesis of monosubstituted succinaldehydes and 3-substituted pyrroles from acetonitriles. Formal synthesis of 2,3-dihydro-7-methyl-2H-pyrrolizidin-1-one (Danaidone), a semiochemical of Danaid butterflies
Mendez, Jose Manuel,Flores, Blas,Leon, Fernando,Martinez, Maria Eugenia,Vazquez, Alfredo,Garcia, Gustavo Alberto,Salmon, Manuel
, p. 4099 - 4102 (2007/10/03)
A convenient and versatile synthesis of monosubstituted succinaldehydes and 3-substituted pyrroles from acetonitriles was devised. The methodology was applied to the preparation of 9, the penultimate intermediate in the Meinwald and Meinwald synthesis of Danaidone.12 Copyright
REDUCTION OF α - SUBSTITUTED SUCCINONITRILES WITH DIISOBUTYLALUMINIUM HYDRIDE: A FACILE METHOD FOR THE SYNTHESIS OF 3-SUBSTITUTED PYRROLES
Babler, James H.,Spina, Kenneth P.
, p. 1659 - 1660 (2007/10/02)
Treatment of four representative α-substituted succinonitriles (2) with diisobutylaluminium hydride, followed by hydrolysis of each reaction mixture with aqueous sodium dihydrogen phosphate, afford 3-substituted pyrroles (4) in approximately 50percent yie
