71847-82-0Relevant academic research and scientific papers
Experimental and DFT study on pyrrole tosylhydrazones
Singh,Rawat, Poonam,Verma, Divya,Bharti, Shailendra Kumar
, p. 543 - 554 (2015)
Two pyrrole tosylhydrazones, 1H-pyrrole-2-tosylhydrazone (PT) and ethyl 3,5-dimethyl-4-(1-(2-tosylhydrazono)ethyl)-1H-pyrrole-2-carboxylate (EDTEPC) have been synthesized and characterized by various spectroscopic techniques. All calculations have been pe
Synthesis and investigation of antimicrobial activity of some nifuroxazide analogues
Alsaeedi, Huda S.,Aljaber, Nabila A.,Ara, Ismet
, p. 3639 - 3646 (2015/12/26)
A series of nifuroxazide analogues [(2a-2e)-(10a-10f)] have been synthesized, structurally identified and tested for antimicrobial activity against a panel of bacteria (Gram-positive and Gram-negative) and the yeast-like pathogenic fungus Candida albicans. The most active compound in this series was 4-amino-benzoic acid (5-nitro-furan-2-ylmethylene)-hydrazide (2b) and 2-amino-benzoic acid (5-nitrofuran-2-ylmethylene)-hydrazide (2d). Furthermore, compounds (9a-9g) and (10a-10g) recorded no activity against selected species except compounds (9f) and (10f) suggesting that using furoic hydrazide and the corresponding hydrazide of thiophene did not improve the antimicrobial activities for this type of compounds. Regarding the activity against Candida albicans, all compounds showed no activity with an exception of substituted nitro furan (2a-2d).
Efficient synthesis of 1,5-disubstituted carbohydrazones using K 2CO3 as a carbonyl donor
Wen, Jun,Yang, Chu-Ting,Jiang, Tao,Hu, Sheng,Yang, Tong-Zai,Wang, Xiao-Lin
supporting information, p. 2398 - 2401 (2014/05/20)
A novel reaction that generates 1,5-disubstituted carbohydrazones via the carbonylation of tosylhydrazones has been developed. For the first time, the inexpensive, readily available, environmentally friendly, and nongaseous potassium carbonate is used as
Alkylation of Aldehyde (Arenesulfonyl)hydrazones with Trialkylboranes
Kabalka, George W.,Maddox, John T.,Bogas, Ekaterini,Kelley, Shane W.
, p. 3688 - 3695 (2007/10/03)
(Arenesulfonyl)hydrazone derivatives of aryl aldehydes are readily alkylated by trialkylboranes in the presence of base to generate new organoboranes that may be converted to the corresponding substituted alkanes or alcohols depending upon the reaction conditions chosen. Both tosyl- and trisylhydrazone derivatives can be utilized in the reaction, which tolerates a variety of functional groups, making it a versatile alternative to both the Grignard and Suzuki-coupling reactions.
