71848-87-8 Usage
Description
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-,2,3-dihydroxypropyl ester is a complex organic compound that is derived from the esterification of 1H-Indole-3-acetic acid with a specific dihydroxypropyl group. This molecule features a unique structure that includes an indole ring, a chlorobenzoyl moiety, and a methoxy group, which may contribute to its potential biological activities and applications.
Uses
Used in Pharmaceutical Industry:
1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-,2,3-dihydroxypropyl ester is used as an anti-inflammatory agent for its potential to modulate inflammatory responses. It has been synthesized and evaluated for its anti-inflammatory activity in the rat paw carrageenan edema assay, which is a common method for assessing the efficacy of compounds in reducing inflammation.
The specific application reason for this compound's use in the pharmaceutical industry is its ability to potentially alleviate inflammation and associated symptoms, making it a candidate for further research and development as a therapeutic agent. Further studies may explore its effectiveness, safety, and potential side effects to determine its suitability as a treatment option for various inflammatory conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 71848-87-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,8,4 and 8 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 71848-87:
(7*7)+(6*1)+(5*8)+(4*4)+(3*8)+(2*8)+(1*7)=158
158 % 10 = 8
So 71848-87-8 is a valid CAS Registry Number.
InChI:InChI=1/C22H22ClNO6/c1-13-18(10-21(27)30-12-16(26)11-25)19-9-17(29-2)7-8-20(19)24(13)22(28)14-3-5-15(23)6-4-14/h3-9,16,25-26H,10-12H2,1-2H3
71848-87-8Relevant articles and documents
Glycerides as prodrugs. 3. Synthesis and antiinflammatory activity of [1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetyl]glycerides (indomethacin glycerides)
Paris,Garmaise,Cimon,Swett,Carter,Young
, p. 9 - 13 (2007/10/02)
Mono-, bis-, and tris[1-(p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetyl]glycerides and 1,3-dialkanoyl-2-[1-p-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetyl]glycerides were synthesized and evaluated for antiinflammatory activity in the rat paw carrag