718604-99-0

Basic information

• Product Name: 4-propyl-phenyl isothiocyanate
• Synonyms: 4-propyl-phenyl isothiocyanate
• CAS NO: 718604-99-0
• Molecular Weight: 177.27
• Mol File: 718604-99-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-propyl-phenyl isothiocyanate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-propyl-phenyl isothiocyanate(718604-99-0)
• EPA Substance Registry System: 4-propyl-phenyl isothiocyanate(718604-99-0)

Safety Data

• Hazardous Substances Data: 718604-99-0(Hazardous Substances Data)

Upstream product

• 2696-84-6 4-propylaniline 
• 463-71-8 thiophosgene 
• 738-85-2 bis-(4-propyl-phenyl)-carbodiimide 
• 854906-55-1 N,N'-bis-(4-propyl-phenyl)-thiourea 
• 96989-50-3 di-2-pyridyl thionocarbonate 

Downstream Products

• 1383478-81-6 C₂₈H₃₂N₂OS 
• 101289-80-9 N-phenyl-N'-(4-propyl-phenyl)-thiourea 

Relevant articles and documents

Synthesis and antimicrobial activity of some new 1,2,4-trizoles

A series of 1,2,4-triazole derivatives were synthesized using appropriate synthetic route and structures were confirmed by IR,1H NMR and elemental analysis. All the synthesized compounds (6a-6h and 7a-7h) were evaluated for antimicrobial activity by determining their minimum inhibitory concentrations (MICs) against a panel of Gram-positive, Gram-negative bacteria and fungi. Most of the compounds showed significant antimicrobial activity against Gram-positive bacteria viz. S. aureus, B. subtilis, Gram-negative bacteria viz. E. coli, P. aerugenosa and fungi viz. C. albicans, A. niger. Some of the compounds showed better antibacterial activities against Gram-positive bacteria compared to Gram-negative bacteria. Compounds 7g, 6g, 6a exhibited good MICs against Gram-positive bacteria and 7f showed better MICs against Gram-negative bacteria compared to reference norfloxacin. Compounds 7f and 7d exhibited MICs which is equipotent to the reference drug ketoconazole.

2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 2: Orally bioavailable compounds

Structure-activity relationships and efforts to optimize the pharmacokinetic profile of a class of 2-arylimino-5,6-dihydro-4H-1,3-thiazines as cannabinoid receptor agonists are described. Among the compounds examined, compound 14 showed potent affinity and high selectivity for CB2, and compound 23 showed potent affinities against CB1 and CB2. These compounds displayed oral bioavailability.