718606-54-3

Upstream product

• 718606-52-1 N-[2-(tert-butyl-dimethyl-silanyloxy)-ethyl]-N-(10-cyano-1-propyl-dec-6-enyl)-4-methyl-benzenesulfonamide 
• 115510-47-9 7-propyl-2-oxepanone 
• 7743-27-3 (4-cyanobutyl)triphenylphosphonium bromide 
• 1026297-74-4 (Z)-(R)-11-[(2-Hydroxy-ethyl)-(toluene-4-sulfonyl)-amino]-tetradec-5-enoic acid 

Downstream Products

• 147363-82-4 (R)-(-)-epilachnene 

Relevant academic research and scientific papers

A modified thermodynamically controlled deracemization of 2-allylcyclohexanone and its application to asymmetric synthesis of (R)-(-)-epilachnene

The efficiency of thermodynamically controlled deracemization was influenced considerably by the solvent used. Based on this finding, an improved method was developed, by which 2-allylcyclohexanone was converted to the R-isomer of 93% ee in 72% yield. As an application of the method, (R)-(-)-epilachnene, an antipode of the defensive droplets from the Mexican bean beetle, Epilachna varivestis, was synthesized in short steps.