718615-35-1Relevant academic research and scientific papers
Catalytic asymmetric conjugate boration of α,β-unsaturated sulfones
Moure, Abraham L.,Gomez Arrayas, Ramon,Carretero, Juan C.
supporting information; experimental part, p. 6701 - 6703 (2011/07/30)
The α,β-unsaturated sulfones are suitable activated olefins in catalytic asymmetric conjugate β-boration. These substrates undergo smooth conjugate addition of bis(pinacolato)diboron [B2(pin)2] catalyzed by nonracemic CuI-diphosphine complexes to provide, upon subsequent oxidation, β-hydroxy sulfones in good yields and high enantiocontrol.
Catalytic asymmetric conjugate addition of Grignard reagents to α,β-unsaturated sulfones
Bos, Pieter H.,Minnaard, Adriaan J.,Feringa, Ben L.
supporting information; experimental part, p. 4219 - 4222 (2009/06/06)
(Chemical Equation Presented) A highly efficient method is reported for the asymmetric conjugate addition of Grignard reagents to α,β- unsaturated 2-pyridylsulfones. Using a Cu/TolBinap complex, excellent enantioselectivities and high yields are obtained
Radical-mediated silyl- and germyldesulfonylation of vinyl and (α-fluoro)vinyl sulfones: Application of tris(trimethylsilyl)silanes and tris(trimethylsilyl)germanes in Pd-catalyzed couplings
Wnuk, Stanislaw F.,Garcia Jr., Pedro I.,Wang, Zhizhong
, p. 2047 - 2049 (2007/10/03)
Equation presented. Radical-mediated silyl- and germyldesulfonylations of various vinyl and (α-fluoro)vinyl sulfones with tris(trimethylsilyl)silane and germanium hydrides provide access to vinyl and (α-fluoro)vinyl silanes and germanes. Upon oxidative treatment with hydrogen peroxide in basic aqueous solution, the vinyl tris(trimethylsilyl)silanes and -germanes undergo Pd-catalyzed cross-couplings with aryl halides.
