7187-24-8Relevant academic research and scientific papers
Structure-activity relationships and antiproliferative effects of 1,2,3,4-4H-quinoxaline derivatives as tubulin polymerization inhibitors
Liang, Tingting,Zhou, Xiaomin,Lu, Lu,Dong, Haiyang,Zhang, Yanan,Xu, Yungen,Qi, Jianguo,Zhang, Yahong,Wang, Jianhong
, (2021/03/29)
Colchicine binding site inhibitors (CBSIs) hold great potential for the treatment of various tumors and they can overcome multidrug resistance which the existing tubulin inhibitors such as paclitaxel and vinorelbine are faced with. Herein, we report the d
Synthesis and Structure - Activity Relationships of Novel Benzimidazole and Imidazopyridine Acid Derivatives as Thromboxane A2 Receptor Antagonists
Nicolai, Eric,Goyard, Joel,Benchetrit, Thierry,Teulon, Jean-Marie,Caussade, Francois,et al.
, p. 1176 - 1187 (2007/10/02)
A series of 1-benzylbenzimidazole and 3-benzylimidazopyridine substituted in the 2-position by an alkanoic or mercaptoalkanoic acid chain was synthesized for evaluation as potential thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonists.T
