7189-17-5

Basic information

• Product Name: ethyl 1-benzyl-3-phenyl-1H-pyrazole-4-carboxylate
• Synonyms: ethyl 1-benzyl-3-phenyl-1H-pyrazole-4-carboxylate
• CAS NO: 7189-17-5
• Molecular Formula: C₁₉H₁₈N₂O₂
• Molecular Weight: 306.35842
• Mol File: 7189-17-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 1-benzyl-3-phenyl-1H-pyrazole-4-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 1-benzyl-3-phenyl-1H-pyrazole-4-carboxylate(7189-17-5)
• EPA Substance Registry System: ethyl 1-benzyl-3-phenyl-1H-pyrazole-4-carboxylate(7189-17-5)

Safety Data

• Hazardous Substances Data: 7189-17-5(Hazardous Substances Data)

Upstream product

• 66129-60-0 ethyl-3-(dimethylamino)-2-(phenylcarbonyl)prop-2-enoate 
• 1073-62-7 N-benzylhydrazine hydrochloride 

Relevant articles and documents

CYCLIC AMINE COMPOUND AND USE THEREOF

The present invention relates to a compound represented by the formula:( I ) wherein ring A is a 5- or 6-membered aromatic heterocycle optionally having substituent (s); U, V and W are each independently C or N, provided that when any one of U, V and W is N, then the others should be C; Ra and Rb are each independently a cyclic group optionally having substituent (s), a C1-10 alkyl group optionally having substituent (s), a C2-10 alkenyl group optionally having substituent (s), or a C2-10alkynyl group optionally having substituent (s); X is a bond, or a spacer having 1 to 6 atoms in the main chain; Y is a spacer having 1 to 6 atoms in the main chain; Rc is a hydrocarbon group optionally containing heteroatom(s) as the constituting atom(s), which optionally has substituent (s); m and n are each independently 1 or 2; and ring B optionally further has substituent (s), or a salt thereof. The compound of the present invention has excellent renin inhibitory activity, and thus is useful as an agent for the prophylaxis or treatment of hypertension, various organ damages attributable to hypertension, and the like.