7190-89-8

Usage

Explanation

The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 11 carbon (C) atoms, 8 hydrogen (H) atoms, 6 nitrogen (N) atoms, and 1 oxygen (O) atom.

Explanation

This term describes the specific arrangement of atoms and bonds in the compound, which is crucial for its chemical properties and reactivity.

Explanation

The compound is used in the synthesis of other organic compounds and is also studied for its potential applications in the development of new drugs.

Explanation

Due to its ability to modulate biological processes, 1,2,4-Triazolo[4,3-b]pyridazin-6(5H)-one, 3-phenyl-, hydrazone is considered a promising candidate for the development of new pharmaceuticals.

Explanation

The compound is a subject of interest in the field of medicinal chemistry, which focuses on the design, development, and study of chemical compounds that can be used as drugs.

Explanation

Given its potential applications in drug development and its unique chemical properties, 1,2,4-Triazolo[4,3-b]pyridazin-6(5H)-one, 3-phenyl-, hydrazone is considered a promising candidate for further research and development in the field of medicinal chemistry.

Chemical Structure

1,2,4-Triazolo[4,3-b]pyridazin-6(5H)-one, 3-phenyl-, hydrazone

Type of Compound

Hydrazone derivative

Application

Organic synthesis and pharmaceutical research

Potential Applications

Development of new drugs

Field of Study

Medicinal chemistry

Status

Promising candidate for further study and exploration

Upstream product

• 7190-80-9 6-Chloro-3-phenyl-s-triazolo<4,3-b>pyridazine 

Downstream Products

• 7190-99-0 1,8-Diphenyl-bis-s-triazolo<4,3-b;3',4'-f>pyridazine 
• 146858-69-7 (E)-2-Methyl-3-(9-oxo-1-phenyl-9H-2,3,6,7,9a,9b-hexaaza-cyclopenta[a]naphthalen-8-yl)-acrylic acid ethyl ester 
• 107263-09-2 ethyl-<3-(6H-6-oxo-3-phenyl-1,2,4-triazino<4,3-b>1,2,4-triazolo<3,4-f>pyridazinyl-7)-2-methacrylate> 
• 107263-06-9 1-(1-ethoxycarbonylethylene)-2-(3-phenyl-1,2,4-triazolo<4,3-b>pyridazinyl-6)-hydrazine 
• 146858-63-1 2-[(3-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-hydrazono]-propionic acid ethyl ester 

Relevant academic research and scientific papers

Synthesis and structural studies of 3,6-disubstituted-bis-1,2,4-triazolo-[4,3-b][3′,4′-f]pyridazines

Synthesis of a series of 3,6-disubstituted-bis-1,2,4-triazolo-[4,3-b][3′,4′-f]pyridazines (4) was accomplished by the oxidative intramolecular cyclization of 6-arylidenehydrazino-3-aryl-1,2,4-triazolo[4,3-b]pyridazine (3) using iodobenzene diacetate (IBD), as a green oxidant, in dichloromethane at room temperature. The compounds 3 and 4 were characterized by IR, NMR (1H and13C), mass spectral data and elemental analyses. X-ray crystal analysis of sterically strained 3,6-di-(2′-fluorophenyl)-bis-1,2,4-triazolo-[4,3-b][3′,4′-f]pyridazine 4f and 3,6-di-(4′-fluorophenyl)-bis-1,2,4-triazolo-[4,3-b][3′,4′-f]pyridazine 4g indicated that pyridazine ring has twisted conformation leading to nonplanar tricyclic core. Both compounds crystallized in orthorhombic P212121 space group, containing one single molecule per asymmetric unit. The studies reveal that the compound 4f is associated with weak, centrosymmetric F?F interactions (distance of 2.882(3) ?), with cis geometry, between adjacent molecules which are responsible for the formation of chains along a axis. Additionally, compounds 4 were screened for their cytotoxic activity against the human cervical carcinoma (HeLa) cell line using MTT assay, however, with not much significant activity.