71907-25-0Relevant academic research and scientific papers
Br?nsted acid-catalysed conjugate addition of photochemically generated α-amino radicals to alkenylpyridines
Hepburn, Hamish B.,Melchiorre, Paolo
supporting information, p. 3520 - 3523 (2016/03/04)
The conjugate addition of α-amino radicals to alkenylpyridines has been accomplished by the synergistic merger of Br?nsted acid and visible light photoredox catalysis. Key to reaction development was the protonation of the alkenylpyridines that transientl
BF3·Et2O-promoted cleavage of the Csp-Csp2 bond of 2-propynolphenols/anilines: Route to C2-alkenylated benzoxazoles and benzimidazoles
Song, Xian-Rong,Qiu, Yi-Feng,Song, Bo,Hao, Xin-Hua,Han, Ya-Ping,Gao, Pin,Liu, Xue-Yuan,Liang, Yong-Min
, p. 2263 - 2271 (2015/03/18)
A novel BF3·Et2O-promoted tandem reaction of easily prepared 2-propynolphenols/anilines and trimethylsilyl azide is developed to give C2-alkenylated benzoxazoles and benzimidazoles in moderate to good yields. Most reactions could be accomplished in 30 min at room temperature. This tandem process involves a Csp-Csp2 bond cleavage and a C-N bond formation. Moreover, both tertiary and secondary propargylic alcohols with diverse functional groups were tolerated under the mild conditions.
Ligand promoted Pd-catalyzed dehydrogenative alkenylation of hetereoarenes
Lee, Wei-Chih,Wang, Ting-Hsuan,Ong, Tiow-Gan
supporting information, p. 3671 - 3673 (2014/04/03)
An efficient Pd-catalyzed cross-dehydrogenative coupling of heteroarenes with styrenes and other olefinic substrates has been developed. This alkenylation paradigm encompasses a wide range of substrates and provides a straightforward approach toward C2-E-alkenylated azole motifs. This journal is the Partner Organisations 2014.
