71916-60-4Relevant academic research and scientific papers
Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents
Abadi, Ashraf H.,Hegazy, Gehan H.,El-Zaher, Asmaa A.
, p. 5759 - 5765 (2007/10/03)
Six derivatives of the general formula 2- or 4-(7-trifluoromethylquinolin- 4-ylamino) benzoic acid N′-(nitrooxyacetyl or propionyl) hydrazide and an oxime of the formula 1-[4-(7-trifluoromethylquinolin-4-ylamino)phenyl]ethanone oxime were synthesized and
7-(Triflluoromethyl)-4-aminoquinoline Hypotensives: Novel Peripheral Sympatholytics
McCall, John M.,TenBrink, R. E.,Kamdar, Bharat V.,Skaletzky, Louis L.,Perricone, Salvatore C.,et al.
, p. 133 - 137 (2007/10/02)
A family of 7-(trifluoromethyl)-4-aminoquinolines that are hypotensive agents and that act by a novel sympatholytic mechanism is described.Structure-activity relationships in this series have been elucidated.Some of the more potent hypotensives were evalu
