71919-14-7

Basic information

• Product Name: Glycine, N,N-dimethyl-, (2,5-dioxo-4,4-diphenyl-1-imidazolidinyl)methyl ester
• CAS NO: 71919-14-7
• Molecular Formula: C20H21N3O4
• Molecular Weight: 367.404
• Mol File: 71919-14-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Glycine, N,N-dimethyl-, (2,5-dioxo-4,4-diphenyl-1-imidazolidinyl)methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Glycine, N,N-dimethyl-, (2,5-dioxo-4,4-diphenyl-1-imidazolidinyl)methyl ester(71919-14-7)
• EPA Substance Registry System: Glycine, N,N-dimethyl-, (2,5-dioxo-4,4-diphenyl-1-imidazolidinyl)methyl ester(71919-14-7)

Safety Data

• Hazardous Substances Data: 71919-14-7(Hazardous Substances Data)

Upstream product

• 57-41-0 phenythoin 
• 1118-68-9 dimethylaminoacetic acid 
• 21616-46-6 3-hydroxymethyl-5,5-diphenyl-imidazolidine-2,4-dione 

Downstream Products

• 71919-15-8 3-(hydroxymethyl)-5,5-diphenylhydantoin N,N-dimethylglycine ester, monomethanesulfonate salt 

Relevant articles and documents

Phenytoin prodrugs III: Water-soluble prodrugs for oral and/or parenteral use

Various bioreversible derivatives of phenytoin, a poorly water soluble and erratically absorbed drug after both oral and parenteral dosing, were synthesized. Initial evaluation of these expected prodrugs, i.e., their aqueous solubility, cleavage in the presence of various animal tissues, and anticonvulsant activity in mice, confirmed that a number of the derivatives did indeed behave as prodrugs. The more promising prodrugs were the disodium phosphate ester and various amino groups containing acyl esters of 3-(hydroxymethyl)-5,5-diphenylhydantoin.