719288-23-0

Upstream product

• 719288-22-9 4-[3-(2,4-bis-benzyloxy-5-chloro-phenyl)-1-(toluene-4-sulphonyl)-1H-pyrazol-4-yl]-piperazine-1-carboxylic acid tert-butyl ester 
• 74-88-4 methyl iodide 
• 90110-32-0 1-(5-chloro-2,4-dihydroxyphenyl)ethan-1-one 
• 95-88-5 4-Chlororesorcinol 
• 719288-18-3 4-[3-(2,4-bis-benzyloxy-5-chloro-phenyl)-1H-pyrazol-4-yl]-piperazine-1-carboxylic acid tert-butyl ester 
• 719288-17-2 4-[2-(2,4-bis-benzyloxy-5-chloro-phenyl)-2-oxo-ethyl]-piperazine-1-carboxylic acid tert-butyl ester 
• 719288-16-1 1-(2,4-bis-benzyloxy-5-chloro-phenyl)-2-bromo-ethanone 
• 705963-54-8 1-[2,4-bis(benzyloxy)-5-chlorophenyl]ethan-1-one 

Relevant academic research and scientific papers

4-Amino derivatives of the Hsp90 inhibitor CCT018159

Novel piperazinyl, morpholino and piperidyl derivatives of the pyrazole-based Hsp90 inhibitor CCT018159 are described. Structure-activity relationships have been elucidated by X-ray co-crystal analysis of the new compounds bound to the N-terminal domain o