719300-08-0

Basic information

• Product Name: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (5-bromo-3-methyl-pyridin-2-yl)-amide
• Synonyms: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (5-bromo-3-methyl-pyridin-2-yl)-amide
• CAS NO: 719300-08-0
• Molecular Weight: 435.243
• Mol File: 719300-08-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (5-bromo-3-methyl-pyridin-2-yl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (5-bromo-3-methyl-pyridin-2-yl)-amide(719300-08-0)
• EPA Substance Registry System: 4'-trifluoromethyl-biphenyl-2-carboxylic acid (5-bromo-3-methyl-pyridin-2-yl)-amide(719300-08-0)

Safety Data

• Hazardous Substances Data: 719300-08-0(Hazardous Substances Data)

Upstream product

• 3430-21-5 5-bromo-3-methyl-pyridin-2-ylamine 
• 180340-74-3 4'-trifluoromethylbiphenyl-2-carbonyl chloride 

Downstream Products

• 719300-09-1 4'-trifluoromethyl-biphenyl-2-carboxylic acid (5-cyano-3-methyl-pyridin-2-yl)-amide 

Relevant articles and documents

Microsomal Triglyceride transfer protein inhibitor

The present invention provides inhibitors of microsomal triglyceride transfer protein (MTP) and/or apolipoprotein B (Apo B) secretion having Formula (I) which are useful for the treatment of obesity and related diseases, as well as prevention and treatment of atherosclerosis and its clinical sequelae, for lowering serum lipids, and in the prevention and treatment of related diseases. The invention further relates to pharmaceutical compositions comprising the compounds of the present invention and to methods of treating obesity, atherosclerosis, and related diseases and/or conditions with the compounds of the present invention, either alone or in combination with other pharmaceutical agents, including lipid-lowering agents.