719310-30-2Relevant academic research and scientific papers
ANTIBACTERIAL COMPOUNDS
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Page/Page column 96, (2019/05/22)
The present invention relates to compounds of general formula (II),to compositions comprising these compounds and to methods of treating Enterobacteriaceae bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Enterobacteriaceae.
Syntheses and kinetic studies of cyclisation-based self-immolative spacers
Huvelle, Steve,Alouane, Ahmed,Le Saux, Thomas,Jullien, Ludovic,Schmidt, Frédéric
, p. 3435 - 3443 (2017/04/24)
Kinetic analysis of the disassembly of self-immolative spacers based on cyclisation processes was performed. Five compounds were synthesized belonging to two different series, and their kinetic constants were determined. Electron-donating substituents gav
Enantioselective Synthesis of 2,3-Disubstituted Benzomorpholines: Analogues of Lignan Natural Products
Jung, Eun-Kyung,Pilkington, Lisa I.,Barker, David
, p. 12012 - 12022 (2016/12/09)
The enantioselective synthesis of 2,3-disubstituted benzomorpholines, analogues of 1,4-benzodioxane natural products, has been achieved via addition of electron-rich aromatic donors to acyl-iminium ions derived from benzomorpholine aminols. Subsequent mod
BENZOXAZINES AND DERIVATIVES THEREOF AS INHIBITORS OF PI3KS
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Page 38, (2010/02/07)
The present invention provides compounds of Formula (I) wherein W, Q, E, D, A, L, R6, R7, R8, Y, K, R9, R10,G, the dashed bond between D and E, and the double bond denoted "*" have any of the values defined therefore in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (I).
