719311-30-5

Basic information

• Product Name: 2-(2,5-dihydroxy-phenylsulfanyl)-3-phenyl-1-(4-triisopropylsilanyloxy-phenyl)-propan-1-one
• CAS NO: 719311-30-5
• Molecular Weight: 522.781
• Mol File: 719311-30-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2,5-dihydroxy-phenylsulfanyl)-3-phenyl-1-(4-triisopropylsilanyloxy-phenyl)-propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,5-dihydroxy-phenylsulfanyl)-3-phenyl-1-(4-triisopropylsilanyloxy-phenyl)-propan-1-one(719311-30-5)
• EPA Substance Registry System: 2-(2,5-dihydroxy-phenylsulfanyl)-3-phenyl-1-(4-triisopropylsilanyloxy-phenyl)-propan-1-one(719311-30-5)

Safety Data

• Hazardous Substances Data: 719311-30-5(Hazardous Substances Data)

Upstream product

• 36941-00-1 1-(4-hydroxyphenyl)-3-phenylpropan-1-one 
• 5739-38-8 1-(4-methoxyphenyl)-3-phenylpropan-1-one 
• 719310-84-6 3-phenyl-1-(4-triisopropylsilanyloxy-phenyl)-propan-1-one 
• 13154-24-0 triisopropylsilyl chloride 
• 2889-61-4 2-mercaptobenzene-1,4-diol 
• 719311-06-5 2-bromo-3-phenyl-1-(4-triisopropylsilanyloxy-phenyl)-propan-1-one 

Relevant articles and documents

Estrogen receptor ligands. Part 3: The SAR of dihydrobenzoxathiin SERMs

A series of 3-alkyl, 3-cycloalkyl, and 3-heteroaryl dihydrobenzoxathiin analogs 1 were prepared and evaluated for estrogen/anti-estrogen activity in both in vitro and in vivo models. In general, the compounds were found to exhibit a high degree of selectivity for ERα over ERβ, but were less potent than the original lead compound 1a in the inhibition of estradiol-driven uterine proliferation.