71932-98-4Relevant academic research and scientific papers
Total synthesis of amphidinolide J
Barbazanges, Marion,Meyer, Christophe,Cossy, Janine
supporting information; experimental part, p. 4489 - 4492 (2009/05/26)
(Chemical Equation Presented) The marine natural product amphidinolide J has been synthesized according to a convergent strategy. The key steps of this synthesis include a B-alkyl Suzuki-Miyaura coupling and the addition of an alkynyllithium reagent to a Weinreb amide to build the C4-C5 and C12-C13 bonds, respectively, and a Yamaguchi macrolactonization.
Metal cation-exchanged montmorillonite (Mn+-mont)-catalyzed friedel-crafts acylation of 1-methyl-1-cyclohexene and 1-trimethylsilyl-1- alkynes
Nishimura, Takahiro,Ohtaka, Seiji,Hashimoto, Keiji,Yamauchi, Takayoshi,Hasegawa, Takuji,Imanaka, Kaori,Tateiwa, Jun-Ichi,Takeuchi, Hiroshi,Uemura, Sakae
, p. 1765 - 1766 (2007/10/03)
The acylation of 1-methyl-1-cyclohexene and 1-trimethylsilyl-1-alkynes with acyl chlorides has been investigated in the presence of a variety of metal cation-exchanged montmorillonites (abbreviated as Mn+-monts), where the catalysts are recycla
Efficient methods for the preparation of acetylenic ketones
Verkruijsse, H. D.,Heus-Kloos, Y. A.,Brandsma, I.
, p. 289 - 294 (2007/10/02)
A number of acetylenic ketones RCCC(=O)R' have been obtained in good yields from lithiated acetylenes RCCLi and acetic anhydride, N,N-dimethylacetamide, or N,N-dimethylbenzamide.The most convenient and general method consists of treating alkynylzinc chlorides with acid halides R'C(=O)Cl.Benzoyl chloride (R'=Ph), acryloyl chloride (R'=CH2=CH) and butynoyl chloride (R'=C2H5CC) react only in the presence of a catalytic amount of Pd4.
