7195-27-9 Usage
Originator
Baycaron,Bayer,W. Germany,1967
Uses
Mefruside is a diuretic used for the treatment of edema and hypertension.
Manufacturing Process
By hydrogenation of α-methyl-α-cyanotetrahydrofuran with Raney nickel as catalyst, α-methyl-α-tetrahydrofurfuryl amine is obtained (BP 48°C/12 mm Hg) which is alkylated by dimethyl sulfate to give α-methyl-αtetrahydrofurfurylmethylamine (BP 70°C/40 mm Hg). The amine is then reacted with 4-chloro-3-sulfamyl benzene sulfochloride in the presence of an acid acceptor. The mixture is stirred overnight, the solvent (acetone or pyridine) is driven off under vacuum and the residue is recrystallized from alcohol.
Check Digit Verification of cas no
The CAS Registry Mumber 7195-27-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,9 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 7195-27:
(6*7)+(5*1)+(4*9)+(3*5)+(2*2)+(1*7)=109
109 % 10 = 9
So 7195-27-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H19ClN2O5S2/c1-13(6-3-7-21-13)9-16(2)23(19,20)10-4-5-11(14)12(8-10)22(15,17)18/h4-5,8H,3,6-7,9H2,1-2H3,(H2,15,17,18)