71962-02-2

Basic information

• Product Name: rac-4-(tert-butyl)cyclohexane-trans-1,2-diol
• CAS NO: 71962-02-2
• Molecular Weight: 172.268
• Mol File: 71962-02-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: rac-4-(tert-butyl)cyclohexane-trans-1,2-diol(CAS DataBase Reference)
• NIST Chemistry Reference: rac-4-(tert-butyl)cyclohexane-trans-1,2-diol(71962-02-2)
• EPA Substance Registry System: rac-4-(tert-butyl)cyclohexane-trans-1,2-diol(71962-02-2)

Safety Data

• Hazardous Substances Data: 71962-02-2(Hazardous Substances Data)

Upstream product

• 35376-39-7 cis 4-tert-butylcyclohexen-1-ol 
• 2228-98-0 4-tert-butylcylohexene 
• 17502-34-0 cis-5-tert-butylcyclohex-2-en-1-ol 
• 71962-01-1 (+/-)-trans-4-tert-butylcyclohexene oxide 
• 31062-01-8 (1S,3R)-(-)-cis-3-tert-butylcyclohexyl tosylate 

Relevant articles and documents

Highly trans-selective intramolecular pinacol coupling of dials catalyzed by bulky Cp2TiPh

Cp2Ti(Ph)Cl in the presence of Me3SiCl and Zn provides an effective pinacol coupling catalyst for aromatic and aliphatic aldehydes.

Diastereoselective inter- and intramolecular pinacol coupling of aldehydes promoted by monomeric titanocene(III) complex Cp2TiPh

A monomeric titanocene(III) derivative, Cp2TiPh, effectively promoted the pinacol coupling of both an aromatic aldehyde, benzaldehyde, and an aliphatic aldehyde, 3-phenylpropionaldehyde. The same reactive complex was successfully generated by a catalytic amount of a precursor, Cp2Ti(Ph)Cl, and its stoichiometric amount of Zn. The Cp2TiPh-catalyzed pinacol coupling of benzaldehyde derivatives and aliphatic aldehydes afforded the corresponding 1,2-diols in high yields with moderate to good threo-selectivity. On the other hand, Cp2TiPh-catalyzed pinacol-cyclization of dials gave cyclic 1,2-diols with excellent diastereoselectivity. The extension of this protocol to chiral dials demonstrated that the phenyltitanium complex catalytically transmitted an axial chirality or a central, chirality of the starting dials to the central chirality of the resultant 1,2-diols.

Hydroxy-steroids. XI. The preparation and infrared spectra of vicinal cholestanediols.

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