Cathepsin S is a lysosomal cysteine protease enzyme that plays a crucial role in the immune system and is involved in the degradation of proteins within lysosomes. It is expressed predominantly in antigen-presenting cells, such as macrophages and dendritic cells, and is implicated in various physiological and pathological processes.
71965-46-3
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Basic information
- Product Name: CATHEPSIN S
- Synonyms: CATHEPSIN S;CATHEPSIN S, BOVINE SPLEEN;EC 3.4.22.27;CTSS;FLJ50259;MGC3886;Cathepsin S Active human
- CAS NO:71965-46-3
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: -70°C
- Solubility: N/A
- CAS DataBase Reference: CATHEPSIN S(CAS DataBase Reference)
- NIST Chemistry Reference: CATHEPSIN S(71965-46-3)
- EPA Substance Registry System: CATHEPSIN S(71965-46-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 71965-46-3(Hazardous Substances Data)
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71965-46-3 Usage
Uses
Used in Pharmaceutical Research:Cathepsin S is used as a target enzyme for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. This helps in the development of potential therapeutic agents for various diseases.
Used in Alzheimer's Disease Research:
Active human cathepsin S has been used in research to assess the pathogenesis of Alzheimer's disease, providing insights into the role of this enzyme in neurodegenerative processes.
Used in Drug Development:
Active human cathepsin S has been employed in studies to investigate the optimization of selectivity of Azepanone-based inhibitors, contributing to the development of more effective and targeted drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 71965-46-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,9,6 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.Calculate Digit Verification of CAS Registry Number 71965-46:
(7*7)+(6*1)+(5*9)+(4*6)+(3*5)+(2*4)+(1*6)=153
153 % 10 = 3
So 71965-46-3 is a valid CAS Registry Number.
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71965-46-3Downstream Products
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CATHEPSIN S
