71978-52-4Relevant academic research and scientific papers
Diastereoselective reduction of E and Z α-alkoxyimino-β-ketoesters by sodium borohydride
Correa Jr., Ivan R.,Moran, Paulo J. S.
, p. 14221 - 14232 (1999)
The reduction of (Z)-α-alkoxyimino-β-ketoesters, R1COC(= NOR3)CO2R2 (R1 = Me, Et, MeOCH2, Ph; R2 = Me, Et, PhCH2; R3 = Me, PhCH2) with NaBH4
Aminothiazole substituted penicillins and antibacterial compositions thereof
-
, (2008/06/13)
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt or in-vivo hydrolysable ester thereof: STR1 wherein R1 is hydrogen or an amino protecting group and R is substituted methyl; optionally substituted C2-12 alkyl, alkenyl or alkynyl; carbocyclyl; aryl or heterocyclyl. These compounds have antibacterial properties, and therefore are of use in the treatment of bacterial infections in humans and animals caused by a wide range of organisms.
