72018-32-7Relevant academic research and scientific papers
Design and synthesis of novel anti-hyperalgesic agents based on 6-prenylnaringenin as the T-type calcium channel blockers
Du Nguyen, Huy,Okada, Takuya,Kitamura, Shun,Yamaoka, Sakura,Horaguchi, Yamato,Kasanami, Yoshihito,Sekiguchi, Fumiko,Tsubota, Maho,Yoshida, Shigeru,Nishikawa, Hiroyuki,Kawabata, Atsufumi,Toyooka, Naoki
, p. 4410 - 4427 (2018)
Since 6-prenylnaringenin (6-PNG) was recently identified as a novel T-type calcium channel blocker with the IC50 value around 1 μM, a series of flavanone derivatives were designed, synthesized and subsequently evaluated for T-channel-blocking a
Variations in the chemical shift of the 5-hydroxyl proton of 7-o-prenylated flavanones
Fukai, Toshio,Nomura, Taro
, p. 1361 - 1364 (2007/10/03)
In 1H nmr examination of 6- or 8-prenylated flavanone 7-methyl and 7-prenyl ethers, the signals of hydrogen-bonded hydroxyl proton appeared in relatively narrow region. Relatively large solvent effect was observed on the signal of 6-prenylflavanone 7-methyl and 7-prenyl ethers.
