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Benzenamine, 4-(3,3-dimethyl-1-triazenyl)-, also known as 4-(3,3-dimethyl-1-triazenyl)aniline or sym-triazine, is an organic compound with the chemical formula C9H13N5. It is a derivative of aniline, where a 3,3-dimethyl-1-triazenyl group is attached to the para position of the benzene ring. Benzenamine, 4-(3,3-dimethyl-1-triazenyl)- is characterized by its potential as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyes. It is also known for its reactivity in coupling reactions, which makes it a valuable building block in the creation of complex organic molecules. Due to its reactivity and the presence of the triazenyl group, it is important to handle this chemical with care, as it may have potential health and environmental impacts.

7203-94-3

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7203-94-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7203-94-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,0 and 3 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7203-94:
(6*7)+(5*2)+(4*0)+(3*3)+(2*9)+(1*4)=83
83 % 10 = 3
So 7203-94-3 is a valid CAS Registry Number.

7203-94-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-(dimethylaminodiazenyl)aniline

1.2 Other means of identification

Product number -
Other names 1-(4'-Aminophenyl)-3,3-dimethyltriazen

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7203-94-3 SDS

7203-94-3Upstream product

7203-94-3Downstream Products

7203-94-3Relevant academic research and scientific papers

Expedient synthesis and anticancer evaluation of dual-action 9-anilinoacridine methyl triazene chimeras

Walunj, Dipak,Egarmina, Katarina,Tuchinsky, Helena,Shpilberg, Ofer,Hershkovitz-Rokah, Oshrat,Grynszpan, Flavio,Gellerman, Gary

, p. 237 - 252 (2020/08/21)

The efficient synthesis of molecular hybrids including a DNA-intercalating 9-anilinoacridine (9-AnA) core and a methyl triazene DNA-methylating moiety is described. Nucleophilic aromatic substitution (SNAr) and electrophilic aromatic substitution (EAS) reactions using readily accessible starting materials provide a quick entry to novel bifunctional anticancer molecules. The chimeras were evaluated for their anticancer activity. Chimera 7b presented the highest antitumor activity at low micromolar IC50 values in antiproliferative assays performed with various cancer cell lines. In comparison, compound 7b outperformed DNA-intercalating drugs like amsacrine and AHMA. Mechanistic studies of chimera 7b suggest a dual mechanism of action: methylation of the DNA-repairing protein MGMT associated with the triazene structural portion and Topo II inhibition by intercalation of the acridine core.

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