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3-(4-chlorophenyl)-2-(4-methoxyphenyl)prop-2-enenitrile, commonly known as Mexiletine, is a chemical compound with the molecular formula C17H14ClNO. It is a derivative of the local anesthetic lidocaine and is primarily used for the treatment of arrhythmia, specifically ventricular arrhythmias.
Used in Pharmaceutical Industry:
Mexiletine is used as an antiarrhythmic agent for the treatment of arrhythmia, particularly ventricular arrhythmias. It functions by blocking sodium channels in the heart, which helps to stabilize the heart's rhythm and prevent abnormal heartbeats.
Additionally, it is being studied for its potential use in treating neuropathic pain and myotonia, indicating its possible application in pain management and neuromuscular conditions.
Used in Medical Treatments:
Mexiletine is used as a therapeutic agent in medical treatments to manage heart rhythm disorders, providing a crucial intervention for patients suffering from arrhythmias.
It is available in oral capsule form and has been approved for medical use in various countries, including the United States and the United Kingdom, highlighting its established role in healthcare.

72030-12-7

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72030-12-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 72030-12-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,3 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 72030-12:
(7*7)+(6*2)+(5*0)+(4*3)+(3*0)+(2*1)+(1*2)=77
77 % 10 = 7
So 72030-12-7 is a valid CAS Registry Number.

72030-12-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (E)-3-(4-chlorophenyl)-2-(4-methoxyphenyl)prop-2-enenitrile

1.2 Other means of identification

Product number -
Other names (2E)-3-(4-chlorophenyl)-2-(4-methoxyphenyl)prop-2-enenitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72030-12-7 SDS

72030-12-7Relevant academic research and scientific papers

Synthesis, characterisation and photophysical properties of a,a-diaryl-acrylonitrile derivatives

Yue, Youfeng,Fang, Haiyan,Wang, Meijun,Wang, Zhiyuan,Yu, Mingxin

experimental part, p. 377 - 380 (2009/12/25)

a,b-Diarylacrylonitrile derivatives can be prepared by two different routes: (1) the intermolecular condensation of the same arylacetonitriles (2) the condensation of arylaldehydes and arylacetonitriles with a catalytic amount of NaOCH3 at room temperature. Several a,b-diarylacrylonitrile derivatives have been synthesised in this paper and characterised. The UV-vis absorption and photoluminescent (PL) spectra of the products were investigated.

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