72034-29-8

Upstream product

• 83859-73-8 trimethylsilane 
• 34421-94-8 4-bromobenzaldehyde diethyl acetal 
• 64-17-5 ethanol 
• 63697-96-1 4-Ethynylbenzaldehyde 
• 77123-57-0 4-[(trimethylsilyl)ethynyl]bezaldehyde 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 83859-77-2 C₃₀H₁₈O₂ 
• 72735-69-4 1-(p-formylphenylethynyl)-8-iodonaphthalene 
• 72735-68-3 1,8-bis(p-formylphenylethynyl)naphthalene 
• 72022-49-2 1-(p-formylphenylethynyl)-1'-iodoferrocene 
• 72022-48-1 1,1'-bis(p-formylphenylethynyl)ferrocene 
• 1315273-17-6 C₁₈H₂₁F₃O₅ 
• 1315273-19-8 C₁₄H₁₁F₃O₄ 
• 1389898-18-3 2-(p-ethynylphenyl)-(4R,5R)-4,5-di(ethoxycarbonyl)-1,3-dioxolane 
• 1389898-20-7 4,4'-ethynylenedibenzaldehyde bis(diethylacetal) 
• 1389898-17-2 tetraethyl 2,2'-(ethynylene-dibenzene-4,1-diyl)bis[(4R,5R)-1,3-dioxolane-4,5-dicarboxylate] 

Relevant academic research and scientific papers

Direct anodic (thio)acetalization of aldehydes with alcohols (thiols) under neutral conditions, and computational insight into the electrochemical formation of the acetals

A versatile protocol for the production of acetals/thioacetals by means of direct electrochemical oxidation is developed here under neutral conditions, providing (thio)acetals with good functional group tolerance and a wide scope for both aldehydes and (thio)alcohols. DFT calculations reveal that direct electron transfer from the anode plays a key role in carbonyl activation during this acid free acetalization process.

X-ray crystal structures and conformational analysis of cyclic acetals derived from tartaric acid and rigid spacer units

Three tartaric ester and tartaric acid derivatives (1-3) with the hydroxy groups being linked via cyclic acetal (1,3-dioxolane) formation to a rigid core, containing phenyl and ethynyl units, have been synthesized. Their crystal structures are reported, emphasizing the molecular geometry, intermolecular interactions, and the resulting packing motifs. All dioxolane rings present in the crystal structures of 1-3 are analyzed and compared with regard to their conformational behavior. In spite of similar substitution patterns, the dioxolane units adopt different conformations including twist and varying envelope isomers. The crystal structures are dominated by C- H···O (esters 1 and 2) and O-H···O (acid 3) hydrogen bonds, leading to different types of packing motifs being characteristic of strand and layer formation.

C1-symmetric Rh/Phebox-catalyzed asymmetric alkynylation of α-ketoesters

Thinking outside the box: A newly developed C1-symmetric Rh/Phebox complex efficiently catalyzed the asymmetric alkynylation of α-ketoester 1 with various aryl and alkyl substituted terminal alkynes to provide the corresponding chiral tertiary propargylic alcohols with up to 99 % ee (see scheme; TMS=trimethylsilyl). Copyright

Synthesis of Paracyclo(1,8)naphthalenophane and Paracyclo(5,6)acenaphthenophane

Paracycloparacyclo(1,8)naphthalenophan-9-ene-1,17-diyne, paracycloparacyclo(5,6)acenaphthenophan-7-ene, and paracycloparacyclo(5,6)acenaphthenophan-9-ene-1,17-diyne, were synthesized by intramolecular reductive coupling reaction