72036-32-9Relevant academic research and scientific papers
Synthesis of Alkyl 4-Hydroxy-2-alkynoates
Midland, M. Mark,Tramontano, Alfonso,Cable, John R.
, p. 28 - 29 (1980)
The lithium acetylide anion of ethyl or methyl propiolate is readily prepared by the addition of n-butyllithium to ethyl or methyl propiolate at low temperature.The anion rapidly adds to a variety of aldehydes or ketones to give ethyl or methyl 4-hydroxy-2-alkynoates in high yield.
