72045-62-6 Usage
Uses
Used in Pharmaceutical Industry:
1-((4-Oxo-2-phenyl-3,4-dihydro-3-quinazolinyl)acetyl)-3-(m-tolyl)-2-thiourea is used as a potential drug candidate for its antitumor properties. MPTQ has shown promising results in preclinical studies, indicating its potential in the development of new drugs for cancer treatment. Its ability to target and inhibit tumor growth makes it a valuable compound for further research and development in oncology.
Additionally, MPTQ is used as a potential drug candidate for its antimicrobial properties. 1-((4-Oxo-2-phenyl-3,4-dihydro-3-quinazolinyl)acetyl)-3-(m-tolyl)-2-th iourea has demonstrated effectiveness against various infectious diseases in preclinical studies, making it a potential candidate for the development of new drugs to combat antibiotic-resistant bacteria and other pathogens.
Check Digit Verification of cas no
The CAS Registry Mumber 72045-62-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,4 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 72045-62:
(7*7)+(6*2)+(5*0)+(4*4)+(3*5)+(2*6)+(1*2)=106
106 % 10 = 6
So 72045-62-6 is a valid CAS Registry Number.
InChI:InChI=1/C24H20N4O2S/c1-16-8-7-11-18(14-16)25-24(31)27-21(29)15-28-22(17-9-3-2-4-10-17)26-20-13-6-5-12-19(20)23(28)30/h2-14H,15H2,1H3,(H2,25,27,29,31)
72045-62-6Relevant academic research and scientific papers
Synthesis of N-aryl-N'-[2-phenyl-3-quinazolino(3H)-4-one] acylthiourea derivatives as anticonvulsants
Misra,Pandey,Dua
, p. 161 - 167 (2007/10/09)
By the reaction of [2-phenyl-3-quinazolino(3H)-4-one] acyl isothiocyanates and appropriate aryl amines in acetone, 24 new compounds, having a substituted thiourea grouping at the 3-position of the quinazolone moiety, were prepared. All compounds, except two, showed different degrees of protection agsinst pentetrazol induced seizure test on albino mice. While studying the effect of structural variation no definite pattern could be observed due to variations in 1-aryl moiety, but it was generally noticed that the branching or lengthening of 3-acyl chain either diminishes or does not effect the activity.
