72045-68-2 Usage
Uses
Used in Pharmaceutical Industry:
1-(2-(4-Oxo-2-phenyl-3,4-dihydro-3-quinazolinyl)propionyl)-3-phenyl-2-thiourea is used as a potential therapeutic agent for its anti-inflammatory, anti-cancer, and anti-diabetic properties. It modulates various enzymes and signaling pathways, making it a promising candidate for the development of new drugs to treat these conditions.
Further research is required to fully understand the pharmacological properties and potential therapeutic uses of 1-(2-(4-Oxo-2-phenyl-3,4-dihydro-3-quinazolinyl)propionyl)-3-phenyl-2- thiourea, as well as to optimize its efficacy and safety for clinical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 72045-68-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,4 and 5 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 72045-68:
(7*7)+(6*2)+(5*0)+(4*4)+(3*5)+(2*6)+(1*8)=112
112 % 10 = 2
So 72045-68-2 is a valid CAS Registry Number.
InChI:InChI=1/C24H20N4O2S/c1-16(22(29)27-24(31)25-18-12-6-3-7-13-18)28-21(17-10-4-2-5-11-17)26-20-15-9-8-14-19(20)23(28)30/h2-16H,1H3,(H2,25,27,29,31)
72045-68-2Relevant academic research and scientific papers
Synthesis of N-aryl-N'-[2-phenyl-3-quinazolino(3H)-4-one] acylthiourea derivatives as anticonvulsants
Misra,Pandey,Dua
, p. 161 - 167 (2007/10/09)
By the reaction of [2-phenyl-3-quinazolino(3H)-4-one] acyl isothiocyanates and appropriate aryl amines in acetone, 24 new compounds, having a substituted thiourea grouping at the 3-position of the quinazolone moiety, were prepared. All compounds, except two, showed different degrees of protection agsinst pentetrazol induced seizure test on albino mice. While studying the effect of structural variation no definite pattern could be observed due to variations in 1-aryl moiety, but it was generally noticed that the branching or lengthening of 3-acyl chain either diminishes or does not effect the activity.
