72045-76-2 Usage
Chemical structure
A derivative of phenyl-2-thiourea with a quinazoline core and thiourea moiety.
Biological activity
Contains a quinazoline core and thiourea moiety, both of which have shown biological activity in various studies.
Potential applications
Important compound in medicinal chemistry due to its pharmacological properties.
Further research
Warranted to explore its potential as a drug candidate.
Fields of interest
Medicinal chemistry and drug discovery.
Chemical profile
Interesting target for further study in the fields of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 72045-76-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,0,4 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 72045-76:
(7*7)+(6*2)+(5*0)+(4*4)+(3*5)+(2*7)+(1*6)=112
112 % 10 = 2
So 72045-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C27H26N4O2S/c1-18(2)17-23(25(32)30-27(34)28-20-13-7-4-8-14-20)31-24(19-11-5-3-6-12-19)29-22-16-10-9-15-21(22)26(31)33/h3-16,18,23H,17H2,1-2H3,(H2,28,30,32,34)
72045-76-2Relevant academic research and scientific papers
Synthesis of N-aryl-N'-[2-phenyl-3-quinazolino(3H)-4-one] acylthiourea derivatives as anticonvulsants
Misra,Pandey,Dua
, p. 161 - 167 (2007/10/09)
By the reaction of [2-phenyl-3-quinazolino(3H)-4-one] acyl isothiocyanates and appropriate aryl amines in acetone, 24 new compounds, having a substituted thiourea grouping at the 3-position of the quinazolone moiety, were prepared. All compounds, except two, showed different degrees of protection agsinst pentetrazol induced seizure test on albino mice. While studying the effect of structural variation no definite pattern could be observed due to variations in 1-aryl moiety, but it was generally noticed that the branching or lengthening of 3-acyl chain either diminishes or does not effect the activity.
