7211-76-9Relevant academic research and scientific papers
Synthesis of functionalized pyrano[3,2-c]pyridines and their transformations to 4-hydroxy-3[(1E)-N-hydroxyalkanimidoyl]pyridones
El-Essawy, Farag A.,Khattab, Ahmed F.,Zahran, Magdy A.,Gomaa, Sherif H.
, p. 3225 - 3237 (2008/02/12)
Reaction of 4-hydroxy-6-methyl-2(1H)-pyridones 1a and 4-hydroxy-1,6- dimethyl-2(1H)-pyridones 1b with diethyl malonates 2a-e leads to the formation of pyrano[3,2-c]pyridines 4a-j. Degradation of 4a-i affords the corresponding ketones 6a-i. Condensation of ketones 6a-i with hydroxyl amine or phenyl hydrazine hydrochloride is described. Copyright Taylor & Francis Group, LLC.
