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1-(2-Chloroethyl)-3-morpholino-1-nitrosourea, commonly known as Semustine, is a chemotherapeutic agent that belongs to the class of alkylating agents. It is a nitrosourea derivative characterized by its ability to form highly reactive intermediates that can cross-link DNA and inhibit DNA synthesis, thereby damaging the DNA of cancer cells and leading to their death. 1-(2-Chloroethyl)-3-morpholino-1-nitrosourea is known for its effectiveness in treating various types of cancer, although it also has the potential to cause side effects and toxicity.

72122-60-2

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72122-60-2 Usage

Uses

Used in Oncology:
1-(2-Chloroethyl)-3-morpholino-1-nitrosourea is used as an anticancer agent for the treatment of brain tumors and Hodgkin's disease. Its mechanism of action involves the formation of reactive intermediates that cross-link DNA, inhibiting DNA synthesis and ultimately leading to the death of cancer cells. Due to its effectiveness in targeting cancer cells, it is a valuable component in the arsenal of treatments for these specific types of cancer.
Used in Medical Research:
In addition to its direct application in cancer treatment, 1-(2-Chloroethyl)-3-morpholino-1-nitrosourea is also used in medical research to study the effects of alkylating agents on DNA and cancer cell biology. Understanding its mechanism of action can contribute to the development of new and improved cancer therapies.
Used in Drug Development:
The study of 1-(2-Chloroethyl)-3-morpholino-1-nitrosourea's properties and effects on cancer cells can aid in the development of new drugs with similar or improved mechanisms of action. Researchers may use this knowledge to design more targeted and less toxic treatments for cancer patients.

Check Digit Verification of cas no

The CAS Registry Mumber 72122-60-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,1,2 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 72122-60:
(7*7)+(6*2)+(5*1)+(4*2)+(3*2)+(2*6)+(1*0)=92
92 % 10 = 2
So 72122-60-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H13ClN4O3/c8-1-2-12(10-14)7(13)9-11-3-5-15-6-4-11/h1-6H2,(H,9,13)

72122-60-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-chloroethyl)-3-morpholin-4-yl-1-nitrosourea

1.2 Other means of identification

Product number -
Other names 1-(2-Chloroethyl)-3-morpholino-1-nitrosourea

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72122-60-2 SDS

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