7213-65-2

Usage

Uses

Used in Pharmaceutical Industry:
1,4-Dihydro-1,4-methanonaphthalene-5,8-diol diacetate is used as a building block in the synthesis of organic molecules for the development of new pharmaceutical compounds. Its versatile chemical structure allows for the creation of various drug candidates with potential therapeutic benefits.
Used in Antiviral Research:
1,4-Dihydro-1,4-methanonaphthalene-5,8-diol diacetate has been studied for its potential antiviral properties, making it a valuable compound in the search for new antiviral agents. Its ability to inhibit viral replication or interfere with viral life cycles could lead to the development of effective treatments for various viral infections.
Used in Anticancer Research:
In addition to its pharmaceutical applications, 1,4-dihydro-1,4-methanonaphthalene-5,8-diol diacetate has also been investigated for its potential anticancer properties. Its ability to target and inhibit the growth of cancer cells could contribute to the development of novel cancer therapies, offering new treatment options for patients.
Used in Chemical Research:
The unique chemical structure of 1,4-dihydro-1,4-methanonaphthalene-5,8-diol diacetate makes it a valuable compound for chemical research. Its reactivity and solubility properties allow for the exploration of various chemical reactions and the synthesis of new compounds with potential applications in various industries.

InChI:InChI=1/C15H14O4/c1-8(16)18-12-5-6-13(19-9(2)17)15-11-4-3-10(7-11)14(12)15/h3-6,10-11H,7H2,1-2H3/t10-,11+

Upstream product

• 21789-66-2 (4arH.8acH)-1.2.3.4.4a.8a-hexahydro-1c.4c-methano-naphthalene-quinone-(5.8) 
• 108-24-7 acetic anhydride 
• 54353-48-9 1,4,4a,8a-tetrahydro-1,4-methanonaphthalene-5,8-dione 
• 51175-59-8 norbornenoquinone 
• 106-51-4 p-benzoquinone 
• 542-92-7 cyclopenta-1,3-diene 

Downstream Products

• 3090-47-9 p-dihydroxybenzonorbornadiene 
• 209674-48-6 C₂₈H₂₇NO₈ 
• 102659-46-1 (+/-)-4-nitro-benzoic acid-(3c,5,8-trimethoxy-1,2,3,4-tetrahydro-1r,4c-methano-naphthalen-2t-yl ester) 
• 947-58-0 8,11-dimethoxybenzonorbornadiene 

Relevant academic research and scientific papers

Soluble cycloannulated tetroxa[8]circulane derivatives: Synthesis, optical and electrochemical properties, and generation of their robust cation-radical salts

Syntheses of soluble bicycloalkane-annulated tetraoxa[8]circulane derivatives via Lewis acid-catalyzed tetramerization of readily available cycloannulated benzoquinons is described. The ready availability of the soluble circulane derivatives allows the evaluation of their optical and electrochemical properties. These circulanes form stable (isolable) cation-radical salts upon 1-electron oxidation using antimony pentachloride and various aromatic oxidants.

Cycloadditions of isobenzofuran to a constrained template bearing neighboring dienophiles

A high yielding synthesis of the pentacyclic diene-dione 1 has enabled investigation of its reactivity as a double dienophile in Diels- Alder [4+2] cycloadditions with isobenzofuran, leading to novel and highly symmetrical three-sided cavitands 3 and 4.

Stereochemical assignments by PMR spectroscopy: Methoxybromination in norbornene systems

The stereochemistry of methoxybromination of some Diels-Alder adducts with bromine in methanol in the presence of yellow lead oxide/silver nitrate has been studied and assigned with the help of PMR spectroscopy. 6,6-Dimethylfulvene-p-benzoquinone adduct (

Stereochemical Assignments of the Addition of Bromine to Olefinic Bonds in Bicyclic Systems by PMR Spectroscopy

Stereochemistry of bromine addition to the olefinic bonds in cyclopentadiene-p-benzoquinone (I) and anthracene-p-benzoquinone (II), the Diels-Alder adducts and 3',6'-diacetoxybenzonorbornadiene (III) has been assigned with the help of PMR spectroscopy.Cyclopentadiene-p-benzoquinone endo-adduct (I) undergoes exo-cis-addition to yield 5,6-dibromo product (IV) whereas anthracene-p-benzoquinone adduct (II) gives the trans-bromo product (VI).Cyclohexanedione ring of the dienophilic moiety in the latter compound has been proposed a preferred chair-type conformation with two axial bromine atoms on the basis of IR and PMR spectra. 3',6'-Diacetoxybenzonorbornadiene (III) gives the rearranged 2,7-dibromo product (VII).