72142-97-3Relevant academic research and scientific papers
Microwave-accelerated solvent-free synthesis of thioketones, thiolactones, thioamides, thionoesters, and thioflavonoids
Varma, Rajender S.,Kumar, Dalip
, p. 697 - 700 (2008/02/11)
Formula presented An expeditious, solvent-free, and high yield conversion of ketones, flavones, isoflavones, lactones, amides, and esters to the corresponding thio analogues is described utilizing Lawesson's reagent in a process that circumvents the use of dry solvents and excess of the reagent.
Photosensitizers: Comprehensive Photophysics/Photochemistry and Theory of Coumarins, Chromones, their Homologues and Thione Analogues
Becker, Ralph S.,Chakravorti, Sankar,Gartner, Carlos A.,Miguel, Maria de Graca
, p. 1007 - 1020 (2007/10/02)
The photophysical-photochemical behaviour, including absorption spectra, flourescence spectra and lifetimes, phosphorescence spectra, triplet-triplet transient spectra, triplet lifetimes and quantum yields and sensitized singlet oxygen formation and yields, has been determined for many of a group of 22 carbonyl and thione compounds.These includes coumarins, psoralens, chromones and furochromone and their thiones.Many of the thiones were synthesized for the first time.Two types of theoretical calculations were carried out on the majority of the compounds.The principal goals of the research for the thiones, were (1) to produce or improve the photosensitizer capability of the compounds in vivo, (2) to shift the spectra of the compounds to significantly longer wavelength and (3) to increase the triplet and singlet oxygen quantum yields.Most of these have been largely achieved.The photosensitizing abilities of the two thiones have been evaluated using a unique testing technique employing a series of genitically engineered bacteria.
PHOTOBIOLOGICAL PROPERTIES OF FUROTHIOCOUMARINS IN SACCHAROMYCES CEREVISIAE
Juettermann, R.,Averbeck, D.,Averbeck, S.,Bastian, G.,Royer, R.
, p. 3 - 13 (2007/10/02)
Nine furothiocoumarins corresponding to psoralen, 8-methylpsoralen, 3-carbethoxy-8-methylpsoralen, 8-methoxysporalen, pseudosporalen, angelicin, isopseudosporalen, allopsoralen and pseudoisosporalen were synthesized by treating furocoumarins with phosphorus pentasulfide. Photobiological studies on haploid yeast cells (Saccharomyces cerevisiae) revealed that the furocoumarins exert some photoactivity on cell survival and the induction of mitochondrial damage.In most cases, the furothiocoumarins were less active than their furocoumarinic counterparts and exhibited a preference for a monofunctional type of action.A certain photochemotherapeutic activity can be suggested.
