721449-01-0Relevant academic research and scientific papers
Design, synthesis, and structure-activity relationship of new isobenzofuranone ligands of protein kinase C
Baba, Yoshiyasu,Ogoshi, Yosuke,Hirai, Go,Yanagisawa, Takeshi,Nagamatsu, Kumiko,Mayumi, Satoshi,Hashimoto, Yuichi,Sodeoka, Mikiko
, p. 2963 - 2967 (2007/10/03)
Protein kinase C (PKC) is a family of enzymes, which play important roles in intracellular signal transduction. We have designed novel PKC ligands having an isobenzofuranone template, based on the proposed interaction of DAG (1,2-diacyl-sn-glycerol) with
