Ficoll TYPE 70, also known as Ficoll PM 70, is a high molecular weight polyethylene glycol (PEG) derivative that is commonly used in various biotechnological and biomedical applications. It is known for its ability to create a crowded environment in solutions, which can mimic the intracellular environment and affect the behavior of biomolecules.
72146-89-5
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Basic information
- Product Name: FICOLL TYPE 70
- Synonyms: FICOLL(R) 70000;FICOLL TYPE 70;Ficoll?70;FICOLL (R) PM 70;Ficoll 70000;Ficoll(R) PM 70, Poly(sucrose-co-epichlorhydrin);Ficoll PM 70,Ficoll PM 70, Poly(sucrose-co-epichlorhydrin);Ficoll(R) , Type 70
- CAS NO:72146-89-5
- Molecular Formula: NULL
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: H2O: 0.1 g/mL, clear to slightly hazy
- CAS DataBase Reference: FICOLL TYPE 70(CAS DataBase Reference)
- NIST Chemistry Reference: FICOLL TYPE 70(72146-89-5)
- EPA Substance Registry System: FICOLL TYPE 70(72146-89-5)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- F: 3
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 72146-89-5(Hazardous Substances Data)
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72146-89-5 Usage
Uses
Used in Biotechnology and Biomedicine:Ficoll TYPE 70 is used as a macromolecular crowding agent for studying cell volume signaling and protein refolding. It helps researchers understand the effects of molecular crowding on biological processes and can be used to improve the stability and solubility of proteins during purification and refolding processes.
Used in Tissue Engineering:
In the field of tissue engineering, Ficoll PM-70 is utilized to develop, evaluate, and use macromolecular crowding (MMC) systems and configurations. These systems can provide insights into the behavior of cells and biomolecules in a more physiologically relevant environment, ultimately contributing to the development of better tissue engineering strategies.
Used in Macromolecular Conformation Research:
Ficoll TYPE 70 is employed in research focused on the conformation of macromolecules, such as proteins and nucleic acids. By creating a crowded environment, it can help researchers study the effects of molecular crowding on the structure, stability, and function of these macromolecules.
Used in Vitrification Research:
Ficoll PM-70 may also be used in vitrification research, which involves the study of the transition of substances from a liquid to a glassy state. This research can have applications in cryopreservation, material science, and the development of new drug delivery systems.
Check Digit Verification of cas no
The CAS Registry Mumber 72146-89-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,1,4 and 6 respectively; the second part has 2 digits, 8 and 9 respectively.Calculate Digit Verification of CAS Registry Number 72146-89:
(7*7)+(6*2)+(5*1)+(4*4)+(3*6)+(2*8)+(1*9)=125
125 % 10 = 5
So 72146-89-5 is a valid CAS Registry Number.
72146-89-5Upstream product
72146-89-5Downstream Products
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FICOLL TYPE 70
