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2,6-dimethylbenzene-1,4-diamine, also known as 2,6-dimethylaniline or 1,3-dimethyl-2-phenylendiamine, is a chemical compound characterized by the molecular formula C8H12N2. It is a colorless to pale yellow liquid at room temperature, recognized for its role as an intermediate in the production of various chemical products.

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  • 7218-02-2 Structure
  • Basic information

    1. Product Name: 2,6-dimethylbenzene-1,4-diamine
    2. Synonyms: 2,6-dimethylbenzene-1,4-diamine;2,6-DIMETHYL-p-PHENYLENEDIAMINE;1,3-Dimethylbenzene-2,5-diamine;2,6-Dimethyl-1,4-phenylenediamine;m-Xylene-2,5-diamine;2,4-Dimethyl-1,3-benzenediamine;m-Xylene-2,4-diamine;4-Amino-2,6-dimethylaniline
    3. CAS NO:7218-02-2
    4. Molecular Formula: C8H12N2
    5. Molecular Weight: 136.19428
    6. EINECS: 230-608-3
    7. Product Categories: N/A
    8. Mol File: 7218-02-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 282.2 °C at 760 mmHg
    3. Flash Point: 146.9 °C
    4. Appearance: /
    5. Density: 1.076 g/cm3
    6. Vapor Pressure: 0.0034mmHg at 25°C
    7. Refractive Index: 1.618
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. PKA: 6.10±0.10(Predicted)
    11. CAS DataBase Reference: 2,6-dimethylbenzene-1,4-diamine(CAS DataBase Reference)
    12. NIST Chemistry Reference: 2,6-dimethylbenzene-1,4-diamine(7218-02-2)
    13. EPA Substance Registry System: 2,6-dimethylbenzene-1,4-diamine(7218-02-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 7218-02-2(Hazardous Substances Data)

7218-02-2 Usage

Uses

Used in Dye and Pigment Production:
2,6-dimethylbenzene-1,4-diamine is utilized as an intermediate in the synthesis of dyes and pigments, contributing to the coloration and stability of these products in various applications.
Used in Pharmaceutical Synthesis:
2,6-dimethylbenzene-1,4-diamine serves as a key intermediate in the production of pharmaceuticals, playing a crucial role in the synthesis of various medicinal agents.
Used as a Curing Agent in Epoxy Resins:
2,6-dimethylbenzene-1,4-diamine is employed as a curing agent in epoxy resins, enhancing the hardening process and improving the final properties of the resin, such as strength and durability.
Used in Chemical Industry:
In the chemical industry, 2,6-dimethylbenzene-1,4-diamine is used as a versatile intermediate for the synthesis of a range of chemical products, highlighting its importance in the manufacturing process.

Check Digit Verification of cas no

The CAS Registry Mumber 7218-02-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,1 and 8 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7218-02:
(6*7)+(5*2)+(4*1)+(3*8)+(2*0)+(1*2)=82
82 % 10 = 2
So 7218-02-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H12N2/c1-5-3-7(9)4-6(2)8(5)10/h3-4H,9-10H2,1-2H3

7218-02-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,6-dimethylbenzene-1,4-diamine

1.2 Other means of identification

Product number -
Other names 2,6-dimethyl-p-phenylenediamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7218-02-2 SDS

7218-02-2Relevant articles and documents

Trans-spanned palladium catalyst for mild and efficient amination of aryl halides with benzophenone imine

Grossman, Olga,Rueck-Braun, Karola,Gelman, Dmitri

, p. 537 - 542 (2008/12/21)

A new protocol for palladium-catalyzed Buchwald-Hartwig amination of aryl chlorides and bromides with benzophenone imine as ammonia surrogate is described. The suggested reaction conditions are mild and may therefore be applied to a variety of sensitive starting materials. Georg Thieme Verlag Stuttgart.

1,3-Dihydroxybenzene derivatives and colorants containing said compounds

-

, (2008/06/13)

1,3-Dihydroxybenzene derivatives of general formula (I) or (Ia) or physiologically tolerated, water-soluble thereof wherein R′1 denotes substituted pyridyl group, a pyrimidyl group, a group of formula (IIa) or (IIIa) and the dyeing agents for keratin fibers containing these compounds.

Process for dyeing keratinous fibers with aminoindoles and oxidation dye precursors at basic Ph's and dyeing agents

-

, (2008/06/13)

The invention relates to a process for dyeing keratinous fibres, which consists in applying to these fibres a composition containing, in a suitable medium for dyeing, at least one coupler of formula: STR1 where R1 denotes hydrogen or alkyl, R2 and R3 denote hydrogen, alkyl, COOR' where R' is alkyl or hydrogen, at least one of the groups R2 and R3 denoting hydrogen, R4 denotes hydrogen, alkyl, hydroxyalkyl, polyhydroxyalkyl or aminoalkyl, Z1 and Z2 denote hydrogen, alkyl, hydroxyl, halogen, alkoxy, at least one of the groups Z1 and Z2 is other than hydrogen at least one oxidation dye precursor, at least one oxidizing agent, the pH of the composition applied to the fibres being higher than 7.

Methods for dyeing keratinous fibers with compositions which contain aminoindole couplers, oxidation dye precursors, and oxidizing agents at acid pHs

-

, (2008/06/13)

A method for dyeing keratin fibers, wherein a composition is applied to said fibers which contains, in a suitable dyeing medium, at least one coupler having formula (I) STR1 wherein R1 is hydrogen or alkyl; R2 and R3 are hydrogen, alkyl, COOR', where R' is alkyl or hydrogen; R4 is hydrogen, hydroxyalkyl, alkyl, polyhydroxyalkyl or acetyl or aminoalkyl wherein the amine may be mono- or disubstituted by alkyl; Z1 and Z2 are hydrogen, alkyl, hydroxy, halogen, alkoxy or a salt thereof; at least one precursor of an oxidation hair dye; and at least one oxidizing agent, the pH of the composition applied to the fibers being less than 7.

3-substituted para-aminophenols

-

, (2008/06/13)

The invention concerns the use of a 3-substituted para-aminophenol as an oxidation dye precursor for dyeing keratinous fibres, in particular human hair. The 3-substituted para-aminophenol has formula: STR1 where R1 represents alkyl, alkenyl, mono- or polyhydroxyalkyl, nitrile, cyanoalkyl, halogenoalkyl, aminoalkyl or alkoxyalkyl and R2 represents hydrogen, alkyl or mono- or polyhydroxyalkyl, provided that when R2 is hydrogen R1 is not methyl or trifluoromethyl, and to addition salts thereof with an acid. The invention also concerns dye compositions containing compound (I). The invention further concerns novel 3-substituted para-aminophenols.

Oxidation dye composition for keratinous fibres comprising a para-aminophenol, 2-methyl-5-aminophenol and a para-phenylenediamine and/or a bis(phenylalkylenediamine)

-

, (2008/06/13)

The invention relates to a dyeing composition for keratinous fibres and in particular for human keratinous fibres such as hair, comprising, in a suitable medium for dyeing, at least one oxidation dye precursor chosen from 3-methyl -para-aminophenol, 2-methyl-para-aminophenol and 2-hydroxymethyl-para-aminophenol, and their addition salts with an acid, as coupling agent, at least 2-methyl-5-aminophenol, or one of its addition salts with an acid; and at least one para-phenylenediamine and/or one bis-(phenylalkylenediamine) or one of their addition salts with an acid as oxidation dye precursor.

Oxidation dye composition for keratinous fibres comprising a para-aminophenol, a meta-aminophenol and a para-phenylenediamine and/or a bis(phenylalkylenediamine)

-

, (2008/06/13)

The invention relates to a dyeing composition for keratinous fibres and in particular for human keratinous fibres such as hair, comprising, in a suitable media for dyeing, at least one oxidation dye precursor chosen from 3-methyl-para-aminophenol, 2-methyl-para-aminophenol and 2-hydroxymethyl-para-aminophenol, and their addition salts with an acid; at least one coupling agent chosen from the 2-methyl-5-aminophenols of formula (I): STR1 in which R is methyl, ethyl, β-hydroxyethyl or γ-hydroxypropyl, and their addition salts with an acid; and at least one para-phenylenediamine and/or one bis(phenylalkylenediamine) or one of their addition salts with an acid as oxidation dye precursor.

Process for dyeing keratinous fibers combining isatin or its derivatives with a tri-, tetra- or pentasubstituted aniline or with a bisphenylalkylenediamine, and dyeing agents

-

, (2008/06/13)

The invention relates to a process for dyeing keratinous fibres, comprising the simultaneous or sequential application of a component (A) containing at least one compound of formula (I): STR1 in which: R1 denotes hydrogen, alkyl, acetyl, benzoyl, phenyl or C1 -C4 carboxyalkyl, R2 and R3 denote hydrogen, alkyl, alkoxy, hydroxyalkyl, amino, halogen, nitro, alkylphenyl, phenyl, alkylamino or hydroxyalkylamino, and a component (B) containing at least (i) a compound of formula (II): STR2 in which: Y denotes OH or NR8 R9, R8 and R9, which are identical or different, denote hydrogen, aminoethyl, hydroxyethyl or C1 -C4 alkyl, R4 to R7 independently of each other denote a hydrogen atom, a C1 -C4 alkyl, a chlorine, a C1 -C4 alkoxy, an acetylamino, an aryloxy, not more than two of the groups R4 to R7 denote a hydrogen atom, excluding 2,5-dimethoxy-1,4-diaminobenzene, and the cosmetically acceptable salts, or (ii) a bisphenylalkylenediamine. It also relates to the dyeing agents for implementing it.

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