72180-24-6 Usage
Uses
Used in Pharmaceutical Industry:
(2S,4R)-1-benzyl-2-methyl-4-fluoropyrrolidine-1,2-dicarboxy is used as a potential pharmaceutical compound for its unique structure and properties. The presence of the benzyl, methyl, fluorine, and carboxylic acid groups may contribute to its interaction with biological systems, offering opportunities for the development of new drugs or therapeutic agents.
The specific applications and effects of （2S,4R)-1-benzyl-2-methyl-4-fluoropyrrolidine-1,2-dicarboxy on biological systems would require further research and testing to fully understand its potential and to determine its suitability for various medical uses. The exploration of its pharmacological profile, including its potential as a drug candidate, would involve assessing its bioavailability, efficacy, and safety in preclinical and clinical studies.
Check Digit Verification of cas no
The CAS Registry Mumber 72180-24-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,1,8 and 0 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 72180-24:
(7*7)+(6*2)+(5*1)+(4*8)+(3*0)+(2*2)+(1*4)=106
106 % 10 = 6
So 72180-24-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H16FNO4/c1-14(12(17)18)7-11(15)8-16(14)13(19)20-9-10-5-3-2-4-6-10/h2-6,11H,7-9H2,1H3,(H,17,18)/t11-,14?/m1/s1
72180-24-6Relevant academic research and scientific papers
Synthesis and Pharmacological Activity of Angiotensin Converting Enzyme Inhibitors: N-(Mercaptoacyl)-4-substituted-(S)-prolines
Smith, Elisabeth M.,Swiss, Gerald F.,Neustadt, Bernard R.,Gold, Elijah H.,Sommer, Jane A.,et al.
, p. 875 - 885 (2007/10/02)
The synthesis of a series of N-(mercaptoacyl)-4-substituted-(S)-prolines (2 and 3) is described.These compounds were evaluated in vitro for inhibition of angiotensin-converting enzyme (ACE), and selected compounds were evaluated in vivo for ACE inhibition.The most potent compounds in vitro are 108, 109, 111, 114, and 116, having relative potencies of 1.0, 1.0, 1.3, 1.1, and 2.6 as compared to the potency of captopril.The most potent compounds in vivo intravenously are 108, 111, 114, 116, 117, and 97.
