72183-95-0Relevant academic research and scientific papers
Studies on Terpenoids and Steroids. Part 1. Structures of Six Novel 27-Hydroxy and 6β-Hydroxy Di- and Tri-oxygenated D:A-friedo-Oleanane Triterpenes from Kokoona zeylanica
Gunatilaka, A. A. Leslie,Nanayakkara, N. P. Dhammika,Sultanbawa, M. Uvais S.
, p. 2459 - 2469 (2007/10/02)
The benzene extract of the inner stem bark of Kokoona zeylanica Thwaites (Celastraceae) contains twelve D:A-friedo-oleananes of which nine are new.The new triterpenes have been classified under three series; kokoonol (3,27-dioxy and 3,21,27-trioxy), zeylanol (3,6-dioxy and 3,6,21-trioxy), and kokzeylanol (3,6,27-trioxy and 3,6,21,27-tetraoxy).Six of these triterpenes belonging to the kokoonol and zeylanol series have been identified as 27-hydroxy-D:A-friedo-oleanan-3-one (4) (kokoonol), 27-hydroxy-D:A-friedo-oleanane-3,21-dione (5) (kokoononol), 21α,27-dihydroxy-D:A-friedo-oleanan-3-one (6) (kokoondiol), 6β-hydroxy-D:A-friedo-oleanan-3-one (21) (zeylanol), 6β-hydroxy-D:A-friedo-oleanane-3,21-dione (22) (zeylanonol) and 6β,21β-dihydroxy-D:A-friedo-oleanan-3-one (23) (zeylandiol), by specroscopic methods and chemical interconversions.The biosynthetic significance of 6-hydroxy-D:A-friedo-oleananes is discussed.
