721942-75-2

Upstream product

• 60946-89-6 1-(1-nitro-5,6,7,8-tetrahydro-[2]naphthyl)-ethanone 
• 92952-46-0 1H-6,7,8,9-tetrahydro-benz[g]indole-2,3-dione 
• 1131-63-1 1,2,3,4-tetrahydro-2-naphthoic acid 
• 872798-81-7 1-nitro-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid 

Downstream Products

• 851546-71-9 3-Hydroxy-2-(4-trifluoromethoxy-benzyl)-7,8,9,10-tetrahydro-benzo[h]quinoline-4-carboxylic acid 
• 851546-61-7 2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid 
• 851546-73-1 2-(3,4-Dichlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid 

Relevant academic research and scientific papers

Methods and compositions for selectin inhibition

The present invention relates to the field of anti-inflammatory substances, and more particularly to novel compounds that act as antagonists of the mammalian adhesion proteins known as selectins. In some embodiments, methods for treating selectin mediated disorders are provided which include administration of compound of Formula I: wherein the constituent variables are defined herein.